ABSTRACT
Secondary infections are known complication of viral respiratory infections, often leads to deterioration of the patient. Secondary infections are commonly seen in severe respiratory viral infections.Critically ill novel coronavirus diseased 19 (COVID-19) patients need hospitalization which increases their risk of acquiring secondaryinfections. The practice of empiric antibiotics due to limited diagnostic capabilities of many hospitals has the potential to escalate an already worrisome antimicrobial resistance (AMR) situation. This study is undertaken to find out most effective antibiotic for empirical treatment. We aimed to define the impact of secondary microbial infections on the clinical course inCOVID-19 patients. A retrospective study was carried out for a period of one year at RMCH& RC, Kanpur, and U.P. India. The patients admitted in intensive care units (ICUs) and wards of the hospitals were undertaken. In our study a total of 262SARS CoV-2 positive patient's pulmonary culture were assessed. Out of 262 cases,53 (20.2%) were culture positive.Prevalence of bacterial culture positive was 46(86.8%) and fungal positive culture was 7 (13.2%). The most common bacterial isolate was Klebsiella pneumoniae 18 (39.1%)followed by Acinetobacter baumannii 12(26.1%), Pseudomonas aeruginosa (17.4%), Escherichia coli 6(13.0%), andStaphylococcusaureus2(4.4%).The overall mortality was high among culture positive patients.The antimicrobial susceptibility pattern in K. pneumoniaeshowed highest resistanceagainst commonly used cephalosporins. Predominance of Gram-negative bacteria (GNB) in COVID-19 patients coupled with high rates of resistance to higher generation antimicrobials is an alarming finding. A high rate of mortality in patients with secondary infections warns to improve the infection control practices andantimicrobial stewardship interventions, not only to save patient lives but also prevent drug-resistant, to which the current situation is very conducive. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
ABSTRACT
The revitalization of the global economy after the COVID-19 era presents Environmental Geotechnics with the opportunity to reinforce the need for a change in paradigm toward a green, circular economy and to promote aggressively the use and development of sustainable technologies and management practices. This paper aims to assist in this effort by concentrating on several thematic areas where sustainability solutions and future improvements are sought. These include the re-entry of construction and demolition waste, excavated material, industrial waste, and marine sediments into the production cycle and the reuse of existing foundations. Despite the recent trend in advanced countries toward recycling and waste-to-energy thermal treatment, landfills still constitute the most common municipal solid waste management practice, especially in low-and-middle-income countries, and technological solutions to improve their environmental footprint are presented. At the same time, remediation solutions are required to address the multitude of contaminated sites worldwide. Advanced developments that incorporate environmental, economic, and social dimensions are expounded, together with sustainable ground improvement solutions for infrastructure projects conducted in soft and weak soils. The topic of thermo-active geostructures concludes this paper, where, apart from their infrastructure utility, these structures have the potential to contribute as a renewable energy source. © 2021 ICE Publishing: All rights reserved.
ABSTRACT
This paper reports the impact of coronavirus disease 2019 on the practice and delivery of geotechnical and geoenvironmental engineering (GGE) education modules, including lectures, lab sessions, student assessments and research activities, based on the feedback from faculty members in 14 countries/regions around the world. Faculty members have since adopted a series of contingent measures to enhance teaching and learning experience during the pandemic, which includes facilitating active learning, exploring new teaching content related to public health, expanding e-learning resources, implementing more engaged and student-centred assessment and delivering high-impact integrated education and research. The key challenges that faculty members are facing appear to be how to maximise the flexibility of learning and meet physical distancing requirements without compromising learning outcomes, education equity and interpersonal interactions in the traditional face-to-face teaching. Despite the challenges imposed by the pandemic, this could also be a good opportunity for faculty members obliged to lecture, to rethink and revise the existing contents and approaches of professing GGE education. Three future opportunities namely, smart learning, flipped learning and interdisciplinary education, are identified. The changes could potentially provide students with a more resilient, engaged, interactive and technology-based learning environment. © 2021 ICE Publishing: All rights reserved.
ABSTRACT
Covid-19 is proving to be an unprecedented disaster for human health, social contacts and the economy worldwide. It is evident that SARS-CoV-2 may spread through municipal solid waste (MSW), if collected, bagged, handled, transported or disposed of inappropriately. Under the stress placed by the current pandemic on the sanitary performance across all MSW management (MSWM) chains, this industry needs to re-examine its infrastructure resilience with respect to all processes, from waste identification, classification, collection, separation, storage, transportation, recycling, treatment and disposal. The current paper provides an overview of the severe challenges placed by Covid-19 onto MSW systems, highlighting the essential role of waste management in public health protection during the ongoing pandemic. It also discusses the measures issued by various international organisations and countries for the protection of MSWM employees (MSWEs), identifying gaps, especially for developing countries, where personal protection equipment and clear guidelines to MSWEs may not have been provided, and the general public may not be well informed. In countries with high recycling rates of MSW, the need to protect MSWEs' health has affected the supply stream of the recycling industry. The article concludes with recommendations for the MSW industry operating under public health crisis conditions. © 2021 ICE Publishing: All rights reserved.
ABSTRACT
The huge number of fatalities due to the coronavirus disease 2019 pandemic has imposed an unprecedented pressure on existing burial facilities. Thus, mass burial is being used in different parts of the world to cope with this unusual situation. As a dead body might be contagious for at least hours, if not days, there is a need to manage/design/construct the mass burial considering the safe handling of coffins and other environmental, social, economical and ethical/dignity aspects. However, the guidelines of the World Health Organization do not thoroughly address the potential risk associated with groundwater pollution due to mass burial construction. Hence, the present study discusses the potential risk of groundwater pollution in mass burial sites and sheds light on the factors that control the survival/retention of bacteria and viruses in porous media. Furthermore, using the available knowledge on designing/monitoring of municipal/industrial waste disposal sites, a cost-effective and simple construction method of mass burial is proposed to mitigate its potential environmental impact. © 2021 ICE Publishing: All rights reserved.
ABSTRACT
The coronavirus disease 2019 pandemic has posed severe threats to humans and the geoenvironment. The findings of severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2) traces in waste water and the practice of disinfecting outdoor spaces in several cities in the world, which can result into the entry of disinfectants and their by-products into storm drainage systems and their subsequent discharge into rivers and coastal waters, raise the issue of environmental, ecological and public health effects. The aims of the current paper are to investigate the potential of water and waste water to operate as transmission routes for Sars-CoV-2 and the risks of this to public health and the geoenvironment. Additionally, several developing countries are characterised by low water-related disaster resilience and low household water security, with measures for protection of water resources and technologies for clean water and sanitation being substandard or not in place. To mitigate the impact of the pandemic in such cases, practical recommendations are provided herein. The paper calls for the enhancement of research into the migration mechanisms of viruses in various media, as well as in the formation of trihalomethanes and other disinfectant by-products in the geoenvironment, in order to develop robust solutions to combat the effects of the current and future pandemics. © 2021 ICE Publishing: All rights reserved.
ABSTRACT
The outbreak of the coronavirus disease 2019 (Covid-19) pandemic not only has created a health crisis across the world but is also expected to impact negatively the global economy and societies at a scale that is maybe larger than that of the 2008 financial crisis. Simultaneously, it has inevitably exerted many negative consequences on the geoenvironment on which human beings depend. The current paper articulates the role of environmental geotechnics in elucidating and mitigating the effects of the current pandemic. It is the belief of all authors that the Covid-19 pandemic presents not only significant challenges but also opportunities for the development of the environmental geotechnics field. This discipline should make full use of geoenvironmental researchers' and engineers' professional skills and expertise to look for development opportunities from this crisis, to highlight the irreplaceable position of the discipline in the global fight against pandemics and to contribute to the health and prosperity of communities, to serve humankind better. In order to reach this goal while taking into account the specificity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the uncertainty of its environmental effects, it is believed that more emphasis should be placed on the following research directions: pathogen-soil interactions;isolation and remediation technologies for pathogen-contaminated sites;new materials for pathogen-contaminated soil;recycling and safe disposal of medical wastes;quantification of uncertainty in geoenvironmental and epidemiological problems;emerging technologies and adaptation strategies in civil, geotechnical and geoenvironmental infrastructures;pandemic-induced environmental risk management;and modelling of pathogen transport and fate in geoenvironment, among others. Moreover, Covid-19 has made it clear to the environmental geotechnics community the importance of urgent international co-operation and of multidisciplinary research actions that must extend to a broad range of scientific fields, including medical and public health disciplines, in order to meet the complexities posed by the Covid-19 pandemic. © 2021 ICE Publishing: All rights reserved.